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Genetic engineering --- Recombinant DNA --- Génie génétique --- ADN recombinant --- Basic Sciences. Molecular Biology --- Genetic Engineering --- Genetic Engineering. --- Génie génétique

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Biotechnologie --- Biotechnology --- Recombinant DNA --- Genetic engineering --- Microorganisms --- ADN recombinant --- Manipulations génétiques --- Micro-organismes --- Industrial application --- Technique --- Safety measures --- Sécurité --- Mesures --- OCDE --- OECD --- ADN --- DNA --- Transformation génétique --- genetic transformation --- safety --- ADN recombiné --- Manipulations génétiques --- Sécurité --- ocde --- adn

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This volume presents a comprehensive collection of detailed state-of-the-art protocols for gapmer-mediated RNA knockdown from leaders in the field. Chapters detail a historical and contemporary perspective of RNase H-inducing antisense oligonucleotides called gapmers and gapmer-mediated RNA knockdown for basic research and therapies. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Gapmers: Methods and Protocols aims to provide diverse applications of gapmers along with protocols that will assist readers in moving the frontier.

ADN --- Àcid desoxiribonucleic --- DNA --- Àcids nucleics --- ADN fòssil --- ADN recombinant --- Elements genètics mòbils --- Gens --- Medical genetics. --- Medical Genetics. --- Clinical genetics --- Diseases --- Heredity of disease --- Human genetics --- Medical sciences --- Pathology --- Genetic disorders --- Genetic aspects

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DNA, Recombinant --- Genetic Engineering --- Genetic engineering --- Recombinant DNA --- Genetic recombination --- Génie génétique --- ADN recombinant --- Recombinaison génétique --- Periodicals. --- Periodicals --- Periodicals --- Périodiques --- Périodiques --- Périodiques

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Molecular biology --- Cloning, Molecular --- DNA, Recombinant --- Molecular cloning --- Recombinant DNA --- Clonage moléculaire --- ADN recombinant --- Génie génétique --- genetic engineering --- ADN --- DNA --- Clonage --- cloning --- Cloning --- Dna --- molecular --- recombinant --- molecular. --- recombinant. --- Molecular. --- Recombinant. --- Clonage moléculaire --- Cloning, Molecular. --- DNA, Recombinant. --- DNA. --- Molecular cloning. --- Recombinant DNA.